UB Care
Additional Warranty can be added to this product for other 12 or 24 months.
Discover more about our warranty policy.

Compact, direct current (DC) Lesion Maker for localized electrolytic lesions in the brain.
Isolated, regulated DC output for electrical safety. Two operating modes: Continuous and Timed.
Features |
Benefit |
---|---|
Current generator protected against short circuit |
Prevents damage to electronics, guarantees safety |
Wide current output range (10uA-99mA) and duration (1-99s) |
Allows for virtually any procedure |
Three Operating Modes |
Continuous, Stand-by and Timed |
Violation LED indicator |
Indicates if compliance is violated |
Operation | |
---|---|
Current Range |
from 10µA to 99mA DC |
Output Voltage |
200V DC +/- 20V |
Max. Electrode Resistance |
20MOhm (10µA) down to 2KOhm (100mA) |
Power Monitoring |
via red LED |
Current Monitoring |
via green LED |
Violation Monitoring |
via yellow LED |
Power Requirement |
115V or 230V, 50/60 Hz, 25W max. |
Operating Mode | Continuous, Timed |
Duration | From 1s to 99s |
Operating Temperature |
10° to 40° C |
Sound Level |
Max 45dB |
Physical | |
Total Weight |
1.4Kg |
Shipping Weight |
3.7Kg approx. |
Dimensions |
27(w)x25(d)x13(h)cm |
Packing Dimensions |
45x34x26cm |
Warranty | |
Warranty |
LMD is covered by a 12-month warranty + 12 after product registration |
UB-Care | Additional UB-Care can be added for other 12 or 24 months |
The surgically or electrically induced lesion has served as an important tool in the experimental search for function in the CNS. Its value has derived in part from the simplicity with which it can be used to study neural mechanisms of behaviour at a basic level.
The advent of the stereotaxic technique, moreover, allowed researchers to produce discretely placed lesions with consistency, especially in subcortical structures of the brain.
The strength of the lesion technique resides also in the variety of ways with which to apply it. Manipulating the type of lesion (DC, RF, knife cut, etc.), its size, the type of electrode, the angle of entry, and so on, should continue to expose critically important aspects of neural functions because of the different effects that are produced.
It is no coincidence that the history of the development of these techniques is closely tied to the recent history of theories regarding localization of function in the brain. The traditional view, whose basic tenets are that (1) the functions are represented in discrete brain structures and that (2) the lesions disrupt function by removal of functional tissue in circumscribed sites, have been recently challenged by growing evidence of the importance of secondary changes.
These are induced by a lesion, both directly (necrosis, anterograde and retrograde degeneration) and indirectly (transneuronal degeneration, regeneration and sprouting, alteration of neurochemical pools, vascular disruption) and may comprise the more significal neurological changes which can account for alteration of behaviour in a lesion experiment.
New strategy of research utilizing lesions is proposed, suggesting that greater emphasis be placed on the a posteriori assessment of secondary changes in the brain as they are correlated with changes in behaviour.
53500 Lesion Making Device, complete with standard accessories | |
---|---|
53500-310 |
Set of 3 output plugs |
E-AU 041 |
USB pen drive, including: 53500-302 Instruction Manual |
Options | |
53500-325 |
Set of 2 Microelectrodes SS Custom FHC for Lesion Making Device, complete with black and red banana plug, and 1 meter cable |
UE(KK1) |
Microelectrode SS Custom FHC (no wires) |
Additional Warranty can be added to this product for other 12 or 24 months.
Discover more about our warranty policy.